‎Journal‎

‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol 509 No 7502 Mai 2014 The Human Proteome‎

‎NPG Nature publishing group. Hardcover. Gut. Policy: An intergovernmental panel on antimicrobial resistance Drug-resistant microbes are spreading. A coordinated global effort is needed to keep drugs working and develop alternatives say Mark Woolhouse and Jeremy Farrar. Health care: Bring microbial sequencing to hospitals Analysing bacterial and viral DNA can help doctors to pick effective drugs quickly says Sharon Peacock. Cosmology: Matter and mixology Francis Halzen is exhilarated by an account of the hunt for the particles of dark matter. Review of The Cosmic Cocktail: Three Parts Dark Matter Katherine Freese Books in brief Q&A: The space crusader US astronomer Neil deGrasse Tyson director of New York s Hayden Planetarium currently hosts the television series Cosmos an update of Carl Sagan s 1980 show broadcast in 181 countries and 45 languages. As it winds down Tyson talks about the rich mix of science and pop culture the neurosynaptic snapshot of public responses to his tweets and his momentous meeting with Sagan. Cancer Herb Brody Statistics: Attacking an epidemic Mike May Therapy: This time it s personal Lauren Gravitz Clinical trials: More trials fewer tribulations Michael Eisenstein Nanotechnology: Deliver on a promise Jessica Wright Comparative biology: Naked ambition Sarah Deweerdt Prevention: Air of danger Rebecca Kessler Developing world: Global warning Eric Bender Bioinformatics: Big data versus the big C Neil Savage Perspective: Learning to share John Quackenbush Biology: Three known unknowns Katherine Bourzac Climate science: A sink down under Daniel B. Metcalfe See also Letter by Poulter et al. Microbiology: Barriers to the spread of resistance Morten O. A. Sommer See also Letter by Forsberg et al. Materials science: Energy storage wrapped up Yury Gogotsi 50 & 100 Years Ago Developmental genetics: Female silkworms have the sex factor Franti ek Marec See also Letter by Kiuchi et al. Precision measurement: The magnetic proton V. Alan Kostelecký See also Letter by Mooser et al. Cardiovascular biology: Switched at birth Katherine E. Yutzey Immunology: To affinity and beyond David M. Tarlinton See also Letter by Gitlin et al. Articles Top A draft map of the human proteome Min-Sik Kim Sneha M. Pinto Derese Getnet Raja Sekhar Nirujogi Srikanth S. Manda et al. A draft map of the human proteome is presented here accounting for over 80% of the annotated protein-coding genes in humans some novel protein-coding regions including translated pseudogenes non-coding RNAs and upstream open reading frames are identified. Mass-spectrometry-based draft of the human proteome Mathias Wilhelm Judith Schlegl Hannes Hahne Amin Moghaddas Gholami Marcus Lieberenz et al. A mass-spectrometry-based draft of the human proteome and a public database for analysis of proteome data are presented assembled information is used to estimate the size of the protein-coding genome to identify organ-specific proteins proteins predicting drug resistance or sensitivity and many translated long intergenic non-coding RNAs and to reveal conserved control of protein abundance. Structural basis of the non-coding RNA RsmZ acting as a protein sponge Olivier Duss Erich Michel Maxim Yulikov Mario Schubert Gunnar Jeschke et al. A novel combined NMR and EPR spectroscopy approach reveals the structure and assembly mechanism of a 70-kDa bacterial ribonucleoprotein complex acting as a protein sponge in translational regulation. Letters Top Three regimes of extrasolar planet radius inferred from host star metallicities Lars A. Buchhave Martin Bizzarro David W. Latham Dimitar Sasselov William D. Cochran et al. Analysis of the metallicities of more than 400 stars hosting 600 candidate extrasolar planets shows that the planets can be categorized by size into three populations terrestrial-like planets gas dwarf planets with rocky cores and hydrogen helium envelopes and ice or gas giant planets on the basis of host star metallicity. Direct high-precision measurement of the magnetic moment of the proton A. Mooser S. Ulmer K. Blaum K. Franke H. Kracke et al. The magnetic moment of the proton is directly measured with unprecedented precision using a double Penning trap. See also News & Views by Kostelecký Contribution of semi-arid ecosystems to interannual variability of the global carbon cycle Benjamin Poulter David Frank Philippe Ciais Ranga B. Myneni Niels Andela et al. The unusually large land carbon sink reported in 2011 can mostly be attributed to semi-arid vegetation growth in the Southern Hemisphere following increased rainfall and long-term greening trends. See also News & Views by Metcalfe Storm-induced sea-ice breakup and the implications for ice extent A. L. Kohout M. J. M. Williams S. M. Dean & M. H. Meylan Concurrent observations at multiple locations indicate that storm-generated ocean waves propagating through Antarctic sea ice can transport enough energy to break first-year sea ice hundreds of kilometres from the ice edge which is much farther than would be predicted by the commonly assumed exponential wave decay. A Palaeozoic shark with osteichthyan-like branchial arches Alan Pradel John G. Maisey Paul Tafforeau Royal H. Mapes & Jon Mallatt A description of the gill skeleton of a very early fossil shark-like fish shows that it bears more resemblance to gill skeletons from bony fishes rather than to those from modern cartilaginous fishes suggesting that modern sharks are not anatomically primitive as previously thought. Bacterial phylogeny structures soil resistomes across habitats Kevin J. Forsberg Sanket Patel Molly K. Gibson Christian L. Lauber Rob Knight et al. Functional metagenomic selections for resistance to 18 antibiotics in 18 different soils reveal that bacterial community composition is the primary determinant of soil antibiotic resistance gene content. See also News & Views by Sommer Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors Srdjan Maksimovic Masashi Nakatani Yoshichika Baba Aislyn M. Nelson Kara L. Marshall et al. The cellular basis of touch has long been debated in particular the relationship between sensory neurons and non-neuronal cells a mouse study uses optogenetics to identify their distinct and collaborative roles with skin-derived Merkel cells both transducing touch and actively tuning responses of touch-sensitive neurons. Piezo2 is required for Merkel-cell mechanotransduction Seung-Hyun Woo Sanjeev Ranade Andy D. Weyer Adrienne E. Dubin Yoshichika Baba et al. A mouse study shows that non-neuronal epidermal Merkel cells aid fine-touch perception in the skin through their expression of the Piezo2 mechanosensitive cation channel which then actively tunes the response to touch in adjacent somatosensory neurons. Scalable control of mounting and attack by Esr1 neurons in the ventromedial hypothalamus Hyosang Lee Dong-Wook Kim Ryan Remedios Todd E. Anthony Angela Chang et al. Activation of Esr1 neurons of the mouse ventromedial hypothalamus initiates graded social behavioural responses weak activation triggers close investigation sniffing during a social encounter that often leads with continued stimulation to mounting behaviours by males towards either gender mounting behaviour transitions to aggressive attacks with greater stimulation intensity. A single female-specific piRNA is the primary determiner of sex in the silkworm Takashi Kiuchi Hikaru Koga Munetaka Kawamoto Keisuke Shoji Hiroki Sakai et al. It is known that in the silkworm Bombyx mori males have two Z sex chromosomes whereas females have Z and W and the W chromosome has a dominant role in female determination here a single female-specific W-chromosome-derived PIWI-interacting RNA is shown to be the feminizing factor in B. mori. See also News & Views by Marec Clonal selection in the germinal centre by regulated proliferation and hypermutation Alexander D. Gitlin Ziv Shulman & Michel C. Nussenzweig Clonal expansion and hypermutation of B cells in the germinal centre are regulated by the amount of antigen that the B cells present to follicular helper T cells. See also News & Views by Tarlinton Dichloroacetate prevents restenosis in preclinical animal models of vessel injury Tobias Deuse Xiaoqin Hua Dong Wang Lars Maegdefessel Joerg Heeren et al. During development of myointimal hyperplasia in human arteries smooth muscle cells have hyperpolarized mitochondrial membrane potential m high proliferation and apoptosis resistance PDK2 is a key regulatory protein whose activation is necessary for myointima formation and its blockade with dichloroacetate prevents m hyperpolarization facilitates apoptosis and reduces myointima formation in injured arteries without preventing vessel re-endothelialization possibly representing a novel strategy to prevent proliferative vascular diseases. gepflegtes Exemplar nur kleine Lesespuren NPG Nature publishing group hardcover‎

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‎Journal fur Schulentwicklung‎

‎3/2014 Kulturelle Bildung‎

‎StudienVerlag. Hardcover. Gut. Inhalt Thema Uwe Hameyer er Marlie Krainz-Dürr Kulturelle Bildung Editorial 4 Michael Wimmer Kulturelle Bildung zwischen traditioneller Randständigkeit und möglicher zentraler Bedeutung für die Schulentwicklung - ein Standortversuch 8 Interview mit Dr. Claudia Schmied geführt von Marlies Krainz-Dürr Kulturelle Bildung aus der Sicht der Schulpolitik 17 Tanja Nagel Was I wir I lernen - ohne es zu merken - Das Potenzial von forschendem Lernen in Kunst und Kultur für Schulentwicklung am Beispiel von Kultur.Forscher! 21 Maren Wichmann & Cornelia Feige Lernen als kulturelle Entdeckungsreise 26 Helene J. Feichter Schülerinnen und Schüler erforschen den Kulturraum Schule 32 Ruth Kunz Die Bedeutung aktiver Rezeption im Kontext fotografischer Bildfindungsprozesse - Ein Projekt der Pädagogischen Hochschule Zürich in Zusammenarbeit mit der Sekundarschule Im Birch 39 Wulf Wersig e7 Karl-Volker Sauer Schulterschluss Schule und Theater 47 Birgit Schüller Was bleibt. Erinnerungen einer Lehrerin 54 gutes Exemplar ordentlich StudienVerlag hardcover‎

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‎Journal fur Schulentwicklung‎

‎1/2010 Re-Vision Schulentwicklung Lernen im Fokus‎

‎StudienVerlag. Hardcover. Gut. Inhalt Thema Marlies Krainz-Dürr er Monica Gather Thurler Re-Vision Schulentwicklung - Lernen im Fokus / Editorial 4 Hans-Günter Rolff Vom Lehren zum Lernen - Von der Notwendigkeit einer pädagogischen Theorie des Lernens 11 Michael Schratz & Tanja Westfall-Greiter Das Dilemma der Individualisierungsdidaktik. Plädoyer für personalisiertes Lernen in der Schule 18 Petra Balke & Peter Daschner Wie LehrerInnen lernen. Aktuelle Herausforderungen in der Lehrerinnenbildung 32 Marlies Krainz-Dürr & Gabriele Khan-Svik Wie Schulen lernen - zur Balance von innerer und äußerer Schulreform am Beispiel des Schulversuchsmodells Neue Mittelschule 40 Monica Gather Thurler & Silvio Herzog Warum widersteht Schulform so hartnäckig allen Entwicklungsabsichten 49 gutes Exemplar ordentlich StudienVerlag hardcover‎

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‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol 516 No. 7529 Dezember 1914 A Quick Look‎

‎NPG Nature publishing group. Hardcover. Gut. EDITORIALS 7 NATURAL RESOURCES The uncertain dash for gas Predictions of fracking s bounty may be on shaky ground 7 SCIENCE AND SOCIETY Harsh reality The postdoc s lot is not a happy one and that needs to change 8 CLIMATE CHANCE Look ahead lt is prudent to research geoengineering strategies even if they won t be used WORLD VIEW n Science should keep out of partisan politics Daniel Sarewitz lt is too simplistic to demonize the right and laud the left SEVEN DAYS 12 THE NEWS IN BRIEF HIV on the rise in Eastern Europe and Central Asia / Polio vaccinators killed in Pakistan /James Watson sells Nobel medal / UK chooses quantum hubs 15 INFECTIOUS DISEASE Race to bring Ebola vaccine to the field gets under way 16 BIOENGINEERING Investigations launched into artificial trachea work 18 PALAEONTOLOGY Meet the fossils challenging Archaeopteryx s status as the first bird 2O CLIMATE CHANCE Researchers thrash out guidelines for geoengineering 21 MEDICAL RESEARCH Initiative aims to träck off-label use of drugs to treat cancer FEATURES 24 PHYSICS Quantum computer quest Thirty years of struggle are finally bearing fruit for quantum computers Sea-level rise and river engineering spell disaster say Liviu Giosan James Syvitski Stefan Constantinescu &John Day BOOKS & ARTS 34 MATHEMATICS Set theory for six-year-olds Alex Bellos 35 BOOKS IN BRIET 36 ROBOTICS Bottom-up innovation Noel Sharkey CORRESPONDENCE 37 Conservation policy debated / New pasture plants or invasive weeds OBITUARY 3B Herman Eisen 1918-2014 Lisa Steiner & Hidde Ploegh 133 INDUSTRY SKILLS Boosting business A number of programmes exist to ease the transition from biomedical trainee to management I35 CAREER BRIEFS TOOLBOX 131 ROBOTICS The automated lab The nature of research is changingas new software and advanced robotics begin to take care of the manual work NEW ONLINE 39 Papers published this week at nature.com NEWS & VIEWS 40 CELL EIETOOL/9A Autophagy transcribed Nuclear receptors control expression of lysosomal and autophagy genes Carmine Settembre & Andrea Ballabio SEE LETTERS R108 & P.112 41 EARTH SCIENCE Controls on isotopic gradients in rain Modelling depletion of heavy isotopes in rain as storms cross land Katherine H Freeman 42 MICROBIOLOGY A backup for bacteria Norovirus infection restores immune development in germ-free mice Yao Wang & Julie K Pfeiffer SEE LETTER R94 44 ASTROPHYSICS Stars fight back A massive galactic outflow of molecular gas in a compact galaxy Philip F Hopkins SEE LETTER R68 45 NEUROBIOLOGY A molecular knife to dice depression A pathway involving 13-catenin and Dicer Proteins may mediate resilience Gerhard Schraff SEE ARTICLE P.51 46 TECHNOLOGY Ultrafast imaging takes on a new design Capturing non-repetitive events at 100 billion frames per second Brian W Pogue SEE LETTER R74 48 BEHAVIOURAL ENADAMS Professional identity can increase dishonesty Banking business culture may weaken employees honesty norms Marie Claire Villeval SEE LETTER P.86 49 DIABETES The good in Tat Fatty acids that enhance glucose uptake from blond in mice Deborah M Muoio & Christopher B Newgard ARTICLES 51 NEUROSCIENCE ß-catenin mediates stress resilience through Dicer1/ A representation of single-shot ultrafast photography at 100 billion frames a second. Gao et al. use compressed imaging with a streak camera to video record non-repetitive transient events in two dimensions with resolution down to tens of picoseconds. PAGES 46 & 74 microRNA regulation C Dias et al. SEE N&V P.45 56 STEM CELLS Deconstructing transcriptional heterogeneity in pluripotent stem cells R M Kumar et al. 62 CELL BIOLOGY Structure of the V. cholerae Na-pumping NADH:quinone oxidoreductase J Steuber et al. LETTERS 68 ASTROPHYSICS Stellar feedback as the origin of an extended molecular outflow in a starburst galaxy J E Geach et al. SEE N&V R44 7I SUPERCONDUCMITY Nonlinear lattice dynamics as a basis for enhanced superconductivity in YBa2Cu306.5 R Mankowsky et al. 74 TECHNOLOGY Single-shot compressed ultrafast photography at one hundred billion frames per second L GaoJ Liang C Li & L V Wang SEE N&V P.46 79 MATERIALS SCIENCE Conductive two-dimensional titanium carbide `clay with high volumetric capacitance M Ghidiu M R Lukatskaya M-Q Zhao Y Gogotsi & M W Barsoum 82 CUMATE Eastern Pacific tropical cyclones intensified by EI Nino delivery of subsurface ocean hegt F-F JinJ. Boucharel & 1-1 Lin 86 BEHAVIOURAL ECONOMICS Business culture and dishonesty in the banking industry A Cohn E Fehr & M A Marechal SEE N&V P.48 90 PLANT SCIENCES Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules X Chen et al. 94 MICROBIOLOGY An enteric virus can replace the beneficial function of commensal bacteria E Kernbauer Y Ding & K Cadwell SEE N&V P.42 99 CELL BIOLOGY The ESCRT machinery regulates the secretion and longrange activity of Hedgehog T Matusek et al. 104 CELL BIOLOGY Centriole amplification by mother and daughter centrioles differs in multiciliated cells A A Jord et al. I08 CELL BIOLOGY Transcriptional regulation of autophagy by an FXR CREB axis S Seok et al. SEE N&V P.40 112 CELL. 810100V Nutrient-sensing nuclear receptors coordinate autophagy M Lee et al. SEE N&V R40 116 CANCER TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein S Bhatnagar et al. 12I NEUROSCIENCE Piezo2 is the major transducer of mechanical Torces for touch sensation in mice SS Ranade et al. 126 NEUROSCIENCE Physical mechanism for gating and mechanosensitivity of the human TRAAK K channel S G Brohawn E B Campbell & R MacKinnon NEUWERTIGkeine LesespurenSEHR SCHÖN NPG Nature publishing group hardcover‎

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‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol. 514 No. 7523 Solar Storm brewing‎

‎NPG Nature publishing group. Hardcover. Gut. EDITORIALS 403 BIOSAFETY A ripe time for gaining ground The frosty debate over gain-of-function work Shows signs of a thaw 403 ANIMAL RESEARCH The ice bucket Success of social-media challenge sidestepped emotive issue 404 ENVIRONMENT Toxic influence Europe raust respond to threat to vultures nosed by livestock drugs. WORLD VIEW 405 Stormy outlook for long-term ecology studies Tim Birkhead Axed guillemot survey raises fears over funders priorities RESEARCH HIGHLIGHTS 406 SELECTIONS FROM THE SCIENTIFIC LITERATURE Sleep loss and obesity / Saving rhinos / Solar corona heating / PhD supply tops demand / Tomadoes clustered SEVEN DAYS 408 THE NEWS IN BRIEF Contentious snails / L Aquila appeal gets under way / Australia boosts ties between science and industry 523 CAREER CHANGES Open for business An MBA can open new career paths for the business-minded scientist 525 TURNING POINT Andrew Dove sees the latest biodegradable polymers as a potential boon to regenerative medicine 411 BIOSECURITY - White House enforces moratorium an gain-of-function research 412 POLITICS US elections hold promise of bleak outlook for science funding 413 ANTHROPOLOGY Oldest genome from modern human gives fresh twist to African exodus 414 ASTRONOMY Solar force offers Kepler telescope new lease of life 416 STRUCTURAL BIOLOGY Protein database wrestles with challenge posed by molecular machines FEATURES 418 RESEARCH The ethics squad Scientists with moral dilemmas dial up ethics consultancies 430 EMERGENCY PLANNING Be prepared Jennifer K Pullium Gordon S Roble & Mark A Raymond Standard emergency preparations tend to fall when the worst happens but there is another way BOOKS & ARTS 432 IN RETROSPECT On the Connexion of the Physical Sciences Richard Holmes CORRESPONDENCE 434 Keep the 2 C climate target / GlobeLand30 mapping for all / Realistic sustainability goals / Research evaluations FUTURES 528 Google car takes the test Norman Spinrad NEW ONLINE 435 Papers published this week at nature.com NEWS & VIEWS 436 CLIMATE CHANCE A crack in the natural-gas bridge Abundant natural gas may have little effect on CO emissions Steven J Davis & Christine Shearer SEE LETTER P.482 437 HIV A stamp on the envelope A high-resolution crystal structure of the pre-fusion Env trimer Rogier W Sanders & John P Moore SEE ARTICLE P.455 438 LUNG DISEASE Treatment by cell transpiant Gene-corrected macrophages treat pulmonary alveolar proteinosis in mice Mary Jane Thomassen & Mani S Kavuru SEE ARTICLE R450 49 ASTRONOM Hurling comets around a planetary nursery Star-grazing comets in the ß Pictoris planetary system form two families Aki Roberge SEE LETTER R462 PHYSIOLOGY Relax and come in Dendritic-cell Signals promote relaxation of lymph-node stromal cells Kari Vaahtomeri & Michael Sixt SEE LETTER R498 42 HIV Potency needs constancy FcyR-mediated effector functions needed for antibody-based viral control Alexandra Trkola ARTICLES 445 GENETICS Genome sequence of a 45000-year-old modern human from western Siberia Q Fu et al. 450 CELL BIOLOGY Pulmonary macrophage transplantation therapy T Suzuki et al. SEE N&V R438 455 IMMUNOLOGY Structure and immune recognition of trimeric pre-fusion HIV-1 Env M Pancera et al. SEE N&V R437 ON THE COVER Solar storm A magnetic model of the Sun before a solar eruption produced by an ejected magnetic rope based on data from the Helioseismic and Magnetic Imager of the NASA Solar Dynamics Observatory mission. Tahar Amari et al. show that the probable driving force for such ejections is the appearance and then the ejection of a `twisted rope of magnetic flux. LETTERS I62 PLANETARY SCIENCE Two families of exocomets in the ß Pictoris system F Kiefer et al. SEE N&V R440 Characterizing and predicting the magnetic environment leading to solar eruptions T Amari A Canou & J-J Aly 170 NANOTECHNOLOLGY Piezoelectricity of single-atomic-layer MoS2 for energy conversion and piezotronics W Wu et al. 175 INORGANIC CHEMISTE Identification of an iridium-containing compound with a formal oxidation state of IX G Wang et al. 178 CLIMATESCIENCF Methane dynamics regulated by microbial community response to permafrost thaw C K McCalley et al. Limited Impact on decadal-scale climate change from increased use of natural gas H McJeon et al. SEE N&V P.436 486 ECOLOGY Producing more grain with lower environmental costs X Chen et al. A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates HJ Parker M E Bronner & R Krumlauf 494 EVOLUTIONARY GENETICS Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis KlBosetal. Dendritic cells control fibroblastic reticular network tension and lymph node expansion S EActon et al. SEE N&V R441 5-Ca Diabetes recovery by age-dependent conversion of pancreatic 8-cells into Insulin producers S Chera et al. High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity MD Schulz et al. 513 CANCER Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia P Ntziachnstos et al. STRUCTURAL BIOLOGY Structure and mechanism of Zn2-transporting P-type ATPases K Wang et al. NEUWERTIGkeine LesespurenSEHR SCHÖN NPG Nature publishing group hardcover‎

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‎Journal fur Schulentwicklung‎

‎2/2012 Schulentwicklung im ganztätigen Lernen‎

‎StudienVerlag. Hardcover. Gut. Inhalt Thema Heinz Günter Holtappels er Marlies Krainz-Dürr Schulentwicklung im ganztägigen Lernen Editorial 4 Wolfram Rollett Lea Spillebeen & Heinz Günter Holtappels Schulentwicklungsprozess an Ganztagsschulen Bedeutung systematischer Qualitätsentwicklung und der Nutzung externer Unterstützung 8 Gabriele Hörl er Elgrid Messner Ansatzpunkte für Schulentwicklung aus der Praxis verschränkter Ganztagsschulen 19 Hans Haenisch Schlüsselfaktoren der Entwicklung offener Ganztagsgrundschulen 25 Ulrike Popp Welche Lehrerinnen braucht die verschränkte Ganztagsschule 33 Wolf Schwarz Qualitätskriterien für Ganztagsschulen - Ein Qualitätsrahmen am Beispiel Hessens 40 Zdenko Medves Länderbericht: Ganztägig Lernen in Slowenien 47 Methodenatelier Anneliese Nageler-Schluga Ratingkonferenz: Zwischen Datenerhebung und Reflexion 51 gutes Exemplar ordentlich StudienVerlag hardcover‎

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‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol 512 No 7513 August The Cop9 Signalosome‎

‎NPG Nature publishing group. Hardcover. Gut. Society: Don t blame the mothers Careless discussion of epigenetic research on how early life affects health across generations could harm women warn Sarah S. Richardson and colleagues. Books and Arts Top History of engineering: Wonder maker Andrew Robinson delves into a study inspired by James Watt s fascinating workshop. Review of James Watt: Making the World Anew Ben Russell Books in brief Barbara Kiser reviews five of the week s best science picks. Neuroscience: What females really want Leslie C. Griffith Solar system: Sandcastles in space Daniel J. Scheeres See also Letter by Rozitis et al. Ageing: Old blood stem cells feel the stress Jiri Bartek & Zdenek Hodny See also Letter by Flach et al. Condensed-matter physics: Glasses made from pure metals Jan Schroers See also Letter by Zhong et al. Cancer: One cell at a time Edward J. Fox & Lawrence A. Loeb See also Article by Wang et al. Astronomical instrumentation: Atmospheric blurring has a new enemy Brent Ellerbroek Structural biology: Corralling a protein-degradation regulator Raymond J. Deshaies See also Article by Lingaraju et al. Limits on fundamental limits to computation Igor L. Markov To evaluate the promise of potential computing technologies this review examines a wide range of fundamental limits such as to performance power consumption size and cost from the device level to the system level. Articles Top Clonal evolution in breast cancer revealed by single nucleus genome sequencing Yong Wang Jill Waters Marco L. Leung Anna Unruh Whijae Roh et al. To investigate genomic diversity within tumours a new type of whole-genome and exome single cell sequencing has been developed using G2/M nuclei the technique was used to sequence single nuclei from an oestrogen-positive breast cancer and a triple-negative ductal carcinoma aneuploidy rearrangements emerged as early events in tumour formation and then point mutations evolved gradually over time. See also News & Views by Fox & Loeb Crystal structure of the human COP9 signalosome Gondichatnahalli M. Lingaraju Richard D. Bunker Simone Cavadini Daniel Hess Ulrich Hassiepen et al. The COP9 signalosome CSN complex regulates cullin RING E3 ubiquitin ligases the largest class of ubiquitin ligase enzymes which are involved in a multitude of regulatory processes here the crystal structure of the entire human CSN holoenzyme is presented. See also News & Views by Deshaies Three-dimensional structure of human -secretase Peilong Lu Xiao-chen Bai Dan Ma Tian Xie Chuangye Yan et al. The three-dimensional structure of intact human -secretase complex at 4.5 Ã… resolution is revealed by cryo-electron-microscopy single-particle analysis the complex comprises a horseshoe-shaped transmembrane domain containing 19 transmembrane segments and a large extracellular domain from nicastrin which sits immediately above the hollow space formed by the horseshoe. Letters Top The origin of the local 1/4-keV X-ray flux in both charge exchange and a hot bubble M. Galeazzi M. Chiao M. R. Collier T. Cravens D. Koutroumpa et al. The contribution of solar-wind ions exchanging electrons with helium and hydrogen near the Sun is shown to be only about 40 per cent of the 1/4-keV X-ray flux observed in the Galactic plane this supports the existence of a local hot bubble filled with X-ray-emitting gas accounting for the rest of the flux. Cohesive forces prevent the rotational breakup of rubble-pile asteroid 29075 1950 DA Ben Rozitis Eric MacLennan & Joshua P. Emery Modelling and observations of the kilometre-sized asteroid 29075 1950 DA reveal it to be a rubble pile that is rotating faster than is allowed by gravity and friction cohesive forces such as those in lunar regolith are required to prevent it breaking up. See also News & Views by Scheeres Formation of monatomic metallic glasses through ultrafast liquid quenching Li Zhong Jiangwei Wang Hongwei Sheng Ze Zhang & Scott X. Mao Metallic liquids of single elements have been successfully vitrified to their glassy states by achieving an ultrafast quenching rate in a new experimental design of which the process has been monitored and studied by a combination of in situ transmission electron microscopy and atoms-to-continuum computer modelling. See also News & Views by Schroers The tidal rotational shape of the Moon and evidence for polar wander Ian Garrick-Bethell Viranga Perera Francis Nimmo & Maria T. Zuber Analysis of the Moon s topography reveals that when its largest basins are removed the lunar shape is consistent with processes controlled by early Earth tides and implies a reorientation of the Moon s principal shape axes. Neuropsychosocial profiles of current and future adolescent alcohol misusers Robert Whelan Richard Watts Catherine A. Orr Robert R. Althoff Eric Artiges et al. Many factors have been proposed as contributors to risk of alcohol abuse but quantifying their influence has been difficult here a longitudinal study of a large sample of adolescents and machine learning are used to generate models of predictors of current and future alcohol abuse assessing the relative contribution of many factors including life history individual personality differences brain structure and genotype. A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes Ida Moltke Niels Grarup Marit E. Jørgensen Peter Bjerregaard Jonas T. Treebak et al. An association mapping study of type-2-diabetes-related quantitative traits in the Greenlandic population identified a common variant in TBC1D4 that increases plasma glucose levels and serum insulin levels after an oral glucose load and type 2 diabetes risk with effect sizes several times larger than any previous findings of large-scale genome-wide association studies for these traits. Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA Emilia Huerta-Sánchez Xin Jin Asan Zhuoma Bianba Benjamin M. Peter et al. Admixture with other hominin species helped humans to adapt to high-altitude environments the EPAS1 gene in Tibetan individuals has an unusual haplotype structure that probably resulted from introgression of DNA from Denisovan or Denisovan-related individuals into humans and this haplotype is only found in Denisovans and Tibetans and at low frequency among Han Chinese. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells Johanna Flach Sietske T. Bakker Mary Mohrin Pauline C. Conroy Eric M. Pietras et al. Haematopoietic stem cell HSC function is known to degrade with age here replication stress is shown to be a potent driver of the functional decline of HSCs during physiological ageing in mice due to decreased expression of mini-chromosome maintenance helicase components and reduced activity of the DNA replication machinery. See also News & Views by Bartek & Hodny Historical contingency and its biophysical basis in glucocorticoid receptor evolution Michael J. Harms & Joseph W. Thornton By characterizing a very large number of might-have-been evolutionary trajectories starting from a resurrected ancestral protein the authors show that the evolution of an essential modern protein was contingent on extremely unlikely historical mutations. DENR MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth Sibylle Schleich Katrin Strassburger Philipp Christoph Janiesch Tatyana Koledachkina Katharine K. Miller et al. This study identifies the DENR MCT-1 complex as the first factors in animals specific for translation re-initiation downstream of upstream Open Reading Frames uORFs. Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA William L. Hwang Sebastian Deindl Bryan T. Harada & Xiaowei Zhuang A nucleosome-spacing mechanism for human ATP-dependent chromatin assembly and remodelling factor ACF. Visualization of arrestin recruitment by a G-protein-coupled receptor Arun K. Shukla Gerwin H. Westfield Kunhong Xiao Rosana I. Reis Li-Yin Huang et al. Single-particle electron microscopy and hydrogen deuterium exchange mass spectrometry are used to characterize the structure and dynamics of a G-protein-coupled receptor arrestin complex. gepflegtes Exemplar nur kleine Lesespuren NPG Nature publishing group hardcover‎

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‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol 512 No. 7515 August 2014 In The Loop‎

‎NPG Nature publishing group. Hardcover. Gut. EDITORIALS 347 SCIENTIFIC ADVICE Diplomatic service Governmental advisers can be crucial in the heat of a crisis 347 CLIMATE CHANCE People power Wanted: models to assess human adaptation to global warming WORLD VIEW 349 AIIow use of electronic cigarettes to assess risk Daniel Sarewitz Research into the health effects of e-cigarettes would waste time and money. Just keep an eye on the users RESEARCH HIGHLIGHTS 35O SELECTIONS FROM THE SCIENTIFIC LITERATURE Opioids from yeast / Meteorites with a history / Coral-averse reefs / Plants novel water supply / Misconduct costed / Lakes by the million / Vaccineresistant polio SEVEN DAYS 352 THE NEWS IN BRIEF Ominous rumblings from lcelandic volcano / Galileo satellites go into wrong orbit / Iran s science minister dismissed / Ice-sheet shrinkage 365 CLIMATE SCINCE Model human adaptation to climate change Paul 1 Palmer & MatthewJ Smith We are adapting to as well as causing environmental change and need to understand the implications 36R ASTROBIOLOGY Cosmic prestige Mario Livio 369 budtire. An Co RIEF 37O FICTION Transgressive treats Paul L McEuen CORRESPONDENCE 371 Supplying China s drinkable water / The eco-friendly dairy farm / Public access to privately owned fossils / Leaming from misconduct cases Mulm nv Peter Marler 1928-2014 Fernando Nottebohm 355 INFECTIOUS DISEASES Agencies call for stronger intemational intervention in Ebola outbreak 357 BIOTECHNOLOGY GM eucalyptus poised for commercial debut in Brazil 35B CONSERVATION Ecotourism not so `eco for whales alter all 359 CLIMATE CHANGE Race is on to record rapidly changing Himalayan vegetation 457 COLUMN zr -- Bold moves Peter Fiske Self-promotion is frowned upon in the academic world but on the butside it can get you noticed and employed 45B CAREER BRIEFS The angle of the light on the bloodstained kitchen floor Matt Mikalatos NEW ONLINE 373 Papers published this week at nature.com NEWS & VIEWS 374 GENOMICS Hiding in plain sight A doubling of data sets from the ENCODE and modENCODE projects Felix Muerdter & Alexander Stark SEE PAGES 393 400 445 449 & 453 375 ASTROPHYSICS Supernova seen through y-ray eyes Evidence that type la supernovae are thermonuclear events Robert P Kirshner SEE LETTER R406 377 IMMUNOLOGY Mammalian watchdog targets bacteria Recognition of virulence factors by the aryl hydrocarbon receptor Parag Kundu & Sven Pettersson SEE ARTICLE P.387 37B NEUTRINO PHYSICS What makes the Sun shine Neutrinos from the nuclear reaction that triggers solar-energy generation Wick Haxton SEE ARTICLE P.383 3BO APPLIED PHYSICS Hybrid sensors ring the changes A highly sensitive optomechanical magnetometer Jörg Wrachtrup & Amit Finkler 3B1 BEHAVIOURAL ECOLOGY Love thy neighbour Enhanced male cooperation may underlie extra-pair mating by females Ben C Sheldon & Marc Mangel ARTICLES 383 PABTICLE PHYSICS Neutrinos from the primary proton proton fusion process in the Sun Borexino Collaboration SEE N&V P.378 387 IMMUNOLOGY AhR sensing of bacterialpigments regulates antibacterial defence P Moura-Alves et al. SEE N&V R377 393 GENOMICS Diversity and dynamics of the Drosophila transcriptome J B Brown et al. SEE N&V R374 4OO GENOMICS Regulatory analysis of the Some new neural activity patterns in learning Rhesus macaques are easier to generate than others corresponding to more easily learned tasks and these can be predicted from network topology at the start of the experiment. This finding could form a basis for a neural explanation for the balance between adaptability and persistence in action and thought. PAGE 423 elegans genome with spatiotemporal resolution C L Araya et al. SEE N&V R374 LETTERS 4O6 ASTROPHYSICS Cobalt-56 y -ray emission lines from the type la supernova 2014J E Churazov et al. SEE N&V P.375 4O9 QUANTUM PHYSICS Quantum imaging with undetected photons G Barreto Lemos et al. 413 ORGANIC CHEMISTRY Carbon carbon bond cleavage and rearrangement of benzene by a trinuclear titanium hydride S Hu T Shima & Z Hou 416 CLIMATE SCIENCE Contrasting responses of mean and extreme snowfall to climate change P A O Gorman 419 EVOLUTION A primitive fish from the Cambrian of North America S Conway Morris & J-8 Caron 423 NEUROSCIENCE Neural constraints an learning P T Sadtler et al. 427 NEUROSCIENCE Processing properties of ON and OFF pathways for Drosophila motion detection R Behnia D A Clark A G Carter T R Clandinin & C Desplan 431 CANCER miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2 J Y Krzeszinski et al. 436 PLANT SCIENCE The long-term maintenance of a resistance polymorphism through diffuse interactions T L Karasov et al. 441 CELL BIOLOGY The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase F Wang C Chan N R Weir & V Denic 445 GENOMICS Comparative analysis of the transcriptome across distant species M B Gerstein et al. SEE N&V P.374 449 GENOMICS Comparative analysis of metazoan chromatin organization J W K Ho et al. SEE N&V P.374 453 GENOMICS Comparative analysis of regulatory information and circuits across distant species A P Boyle et al. SEE N&V R374 QUANTUM PHYSICS Seeing red How to generate quantum images using undetected photons PAGE 409 NEUWERTIGkeine LesespurenSEHR SCHÖN NPG Nature publishing group hardcover‎

Referentie van de boekhandelaar : B00042464

‎Journal fur Schulentwicklung‎

‎4/2009 Empowerment‎

‎StudienVerlag. Hardcover. Gut. Inhalt Thema Monica Gather Thurler & Peter Daschner Empowerment - Editorial 4 Anne Barrere Vom Klassenzimmer zum Schulhaus Bewährungsproben der Lehrerinnenarbeit in Reformzeiten 9 Karl Mäder Empowerment durch Beratung - Professionalisierung von Lehrpersonen und Schulen 18 Georges Pasquier Lehrerinnen brauchen Hoffnung und Freiräume 24 Jean Wagner Eine Schule die die Personalentwicklung ihrer Lehrpersonen ernst nimmt. Ein Praxisbericht 30 Monica Gather Thurler er Laetitia Progin Verteiltes Leadership und Empowerment von Lehrpersonen 37 Reiner Lehberger er Uwe Schaarschmidt Eignungsberatung für Lehramtsstudierende - Rückmeldungen und Angebote zum Kompetenzausbau 46 gutes Exemplar ordentlich StudienVerlag hardcover‎

Referentie van de boekhandelaar : B00051024

‎nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE‎

‎Vol 508 No. 7497 April 2014 Reasons for Y‎

‎NPG Nature publishing group. Hardcover. Gut. Medical genomics: Gather and use genetic data in health care Research into how genetic variants can guide successful treatments must become part of routine medical practice and records says Geoffrey Ginsburg. Books and Arts Top Natural history: A scientist s eye Beatrix Potter s meticulous artistry served mycology and entomology as well as children s fiction reveals Linda Lear. Medicine: The commodified body Scott Carney assesses a study of banked human blood sperm and milk. Review of Banking on the Body: The Market in Blood Milk and Sperm in Modern America Kara W. Swanson Climate science: Stratospheric folly Tim Kruger examines an argument against injecting aerosols into the atmosphere to counter climate change. Review of Can Science Fix Climate Change A Case Against Climate Engineering Mike Hulme Electrochemistry: Catalysis at the boundaries Aaron M. Appel See also Letter by Li et al. Sensory systems: Do you hear what I see Ione Fine Infection biology: Nibbled to death Nancy Guillén See also Letter by Ralston et al. Genetics: The vital Y chromosome Andrew G. Clark See also Article by Cortez et al. See also Article by Bellott et al. 50 & 100 Years Ago Climate science: Sea levels from ancient seashells Ralph Schneider See also Article by Rohling et al. Reproductive biology: Sperm protein finds its mate Paul M. Wassarman See also Article by Bianchi et al. Letters Top Superconducting quantum circuits at the surface code threshold for fault tolerance R. Barends J. Kelly A. Megrant A. Veitia D. Sank et al. A universal set of logic gates in a superconducting quantum circuit is shown to have gate fidelities at the threshold for fault-tolerant quantum computing by the surface code approach in which the quantum bits are distributed in an array of planar topology and have only nearest-neighbour couplings. Electroreduction of carbon monoxide to liquid fuel on oxide-derived nanocrystalline copper Christina W. Li Jim Ciston & Matthew W. Kanan The electrochemical conversion of CO and H2O into liquid fuel is made feasible at modest potentials with the use of oxide-derived nanocystalline Cu as the catalyst. See also News & Views by Appel Hybrid shallow on-axis and deep off-axis hydrothermal circulation at fast-spreading ridges Jörg Hasenclever Sonja Theissen-Krah Lars H. Rüpke Jason P. Morgan Karthik Iyer et al. High-resolution three-dimensional simulations of hydrothermal flow beneath fast-spreading ridges predict two interacting flow components shallow on-axis flow and deeper off-axis flow that merge to feed axial vent sites reconciling previously incompatible models favouring only one flow component. Plate tectonics damage and inheritance David Bercovici & Yanick Ricard Lithospheric damage combined with transient mantle flow and migrating proto-subduction is proposed to explain the apparent emergence of plate tectonics three billion years ago modelling confirms that tectonic plate boundaries and fully formed tectonic plates can arise under conditions characteristic of Earth but not of Venus. Herbivores and nutrients control grassland plant diversity via light limitation Elizabeth T. Borer Eric W. Seabloom Daniel S. Gruner W. Stanley Harpole Helmut Hillebrand et al. Experimental data collected from 40 grasslands on 6 continents show that nutrients and herbivores can serve as counteracting forces to control local plant diversity nutrient addition reduces local diversity through light limitation and herbivory rescues diversity at sites where it alleviates light limitation. Eutrophication weakens stabilizing effects of diversity in natural grasslands Yann Hautier Eric W. Seabloom Elizabeth T. Borer Peter B. Adler W. Stanley Harpole et al. Experimental eutrophication weakens the stabilizing effects of plant diversity on the productivity of natural grasslands. Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion Katherine S. Ralston Michael D. Solga Nicole M. Mackey-Lawrence Somlata Alok Bhattacharya et al. Entamoeba histolytica the causative agent of fatal diarrhoeal disease in children in the developing world is shown here to kill human cells by biting off and ingesting pieces of cells in a process reminiscent of the trogocytosis seen between immune cells ingestion of bites is required for killing and this mechanism is used both in tissue culture and during invasion of intestinal explants. See also News & Views by Guillén Inhibition of miR-25 improves cardiac contractility in the failing heart Christine Wahlquist Dongtak Jeong Agustin Rojas-Muñoz Changwon Kho Ahyoung Lee et al. Reduced activity of the calcium-transporting ATPase SERCA2a is a hallmark of heart failure here microRNAs that downregulate SERCA2a function are identified and antagonism of one miR-25 is shown to halt heart failure in mice. Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation Yoshiki Omatsu Masanari Seike Tatsuki Sugiyama Tsutomu Kume & Takashi Nagasawa Transcription factor Foxc1 is a key regulator of haematopoietic stem/progenitor cell niche formation. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus Pengda Liu Michael Begley Wojciech Michowski Hiroyuki Inuzuka Miriam Ginzberg et al. Phosphorylation of Akt at its carboxy-terminal tail is an essential layer of Akt activation to regulate its physiological functions. Nectar secretion requires sucrose phosphate synthases and the sugar transporter SWEET9 I Winnie Lin Davide Sosso Li-Qing Chen Klaus Gase Sang-Gyu Kim et al. Although nectar is known to be important for example in plant insect interactions little has been known about the mechanism of its secretion sucrose phosphate synthases are now reported to be essential for the synthesis of the sucrose component of nectar and the transporter protein SWEET9 is shown to mediate sucrose export into the extracellular space of the nectary. Structure of a type IV secretion system Harry H. Low Francesca Gubellini Angel Rivera-Calzada Nathalie Braun Sarah Connery et al. The three-dimensional structure of the type IV secretion system encoded by the Escherichia coli R388 conjugative plasmid. gepflegtes Exemplar nur kleine Lesespuren NPG Nature publishing group hardcover‎

Referentie van de boekhandelaar : B00042570

‎Ein urgemutliches sachsisches Journal‎

‎Der kleine Drache Nummer 8‎

‎Hardcover. Gut. INHALT Lutz Lange: Mein buntes deutsches Leipzig / Andreas Reimann: taus der gegenwart / Jochen Meier: Leipzigs Straßen / Reinhard Lochnerz Politische Sprüche / Jürgen Hart: Die letzte Fahrt / Ramona Kraetke: Vorstadtabend / Sepp Sachs: Es braucht alles seine Zeit LEIPZIGER ALLERLEI Hoffnung / Unsere klerikale Frage / Gut gesagt / Im Kaufhaus / ficht zu helfen / Frühkindlicher Fernseh-Schaden / Musik- enner u.a. obias Jurack: Heemebaadn /Gunter Böhnke: Der touristische Sach- Eirtikel / Hans-Walter Molle: In der Kneipe / Hanskarl Hoerning: Kurt besucht die Litfaßsäule / Thomas Reuter: Ich Früchtchen Cartoons und Illustrationen von Matthias Götz und Lothar Otto / Alfred Glaser: Ne schdille Schdunde / Matthias Götz: Herren- gepflegtes Exemplar nur kleine Lesespuren Buchblock altersgemäß gebräunt hardcover‎

Referentie van de boekhandelaar : B00008116

‎T. Thaphada Journal‎

‎Paris Mon Amour A Cook's Journal: 160 Blank Recipe Book 8x10" Blank Recipe Journal/Blank Cookbook/CookbookNote/Recipe Journal / Recipe Notebook / Blank Cook Book - Full Color Cover‎

‎CreateSpace Independent Publishing Platform 2016. Paperback. New. jou edition. 160 pages. 10.00x8.00x0.37 inches. CreateSpace Independent Publishing Platform paperback‎

Referentie van de boekhandelaar : __1541269942 ISBN : 1541269942 9781541269941

‎DIARIO DE NAVARRA‎

‎EL ARTE EN NAVARRA. TOMO 1‎

‎1994. DURA GRAN FORMATO. Bien/Sin cubierta. EL ARTE DE NAVARRA QUE AHORA VE LA LUZ CONSTITUYE EL PRIMER INTENTO DE OFRECER A UN PÚBLICO AMPLIO LOS GRANDES TEMAS DEL ARTE NAVARRO VISTOS DESDE EL ESTADO ACTUAL DE NUESTROS CONOCIMIENTOS E ILUMINADOS POR LOS ÚLTIMOSENFOQUES METODOLÓGICOD DE LA HISTORIOGRAFÃA ARTÃSTICA. hardcover‎

Referentie van de boekhandelaar : 119357alzo ISBN : 8489103011 9788489103016

‎Journal, The‎

‎Q&A a Day for Kids: A five-Year Journal: Create Your Own Personal Time Capsule‎

‎Independently published 2019. Paperback. New. 370 pages. 9.00x6.00x0.84 inches. Independently published paperback‎

Referentie van de boekhandelaar : __1692401742 ISBN : 1692401742 9781692401740

‎Noble Journal‎

‎My Prayer Journal: 100 Days of Prayer Praise and Thanks‎

‎Independently published 2019. Paperback. New. 108 pages. 10.00x8.00x0.25 inches. Independently published paperback‎

Referentie van de boekhandelaar : __1793456666 ISBN : 1793456666 9781793456663

‎Food Editors Of Farm Journal; Elise W. Manning‎

‎Family Favorites from Country Kitchens‎

‎Doubleday & Company. First Edition. Acceptable. The item might be beaten up but readable. May contain markings or highlighting as well as stains bent corners or any other major defect but the text is not obscured in any way. Doubleday & Company unknown‎

Referentie van de boekhandelaar : 038505095X-7-1 ISBN : 038505095x 9780385050951

‎Lincoln Journal Star‎

‎The Best of the Big Red Running Backs‎

‎Sports Pub 1998. Hardcover. Very Good. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More Spend Less.Dust jacket quality is not guaranteed. Sports Pub hardcover‎

Referentie van de boekhandelaar : G1582610010I4N00 ISBN : 1582610010 9781582610016

‎The Staff Of New Orleans' Daily Newspaper‎

‎KATRINA The Ruin and Recovery of New Orleans‎

‎Louisiana: The Times-Picayune 2006. First Edition; First Printing. Hardcover. Near Fine in a Near Fine dust jacket. The Times-Picayune hardcover‎

Referentie van de boekhandelaar : 206388

‎LRB Diary‎

‎LRB Diary for 2026: Brief Lives‎

‎new. unknown‎

Referentie van de boekhandelaar : 50256535-n ISBN : 1913465217 9781913465216

‎The Journal of Short Film 20 (Summer 2010) 2010)‎

‎The Journal of Short Film 20 Summer‎

‎New. unknown‎

Referentie van de boekhandelaar : H-7-5969979995949

‎Diary, LRB (Author)‎

‎LRB Diary for 2026: Brief Lives LRB Diaries‎

‎Profile Books 2025. Hardcover. New. 90 pages. 6.06x0.71x8.35 inches. Profile Books hardcover‎

Referentie van de boekhandelaar : __1913465217 ISBN : 1913465217 9781913465216

‎Keepsake Journal‎

‎Labrador Journal: Blank lined journal Pictures and more‎

‎Independently published 2018. Paperback. New. 98 pages. 10.00x8.00x0.24 inches. Independently published paperback‎

Referentie van de boekhandelaar : __1730843387 ISBN : 1730843387 9781730843389

‎Journal, Comics‎

‎Best Comics of the Decade Volume 2‎

‎Fantagraphics Books Inc. Used - Good. . . All orders guaranteed and ship within 24 hours. Your purchase supports More Than Words a nonprofit job training program for youth empowering youth to take charge of their lives by taking charge of a business. Fantagraphics Books Inc unknown‎

Referentie van de boekhandelaar : WAL-G-1c-002455 ISBN : 0560970374 9780560970371

‎CGT Le Journal Le Peuple‎

‎La CGT et les societes multinationales : supplement au journal Le Peuple No.914 du 16/31 mars 1973‎

‎CGT Le Journal Le Peuple 1973. Staplebound. Very Good. Fascicule broché deux agrafes. 16 x 16 cm 35 pages illustrées en bleu. Bel état usures externes couverture insolée ; intérieur frais et propre vierge d'annotations. Rare <br/> <br/> CGT Le Journal Le Peuple unknown‎

Referentie van de boekhandelaar : 024494

‎The Hero's Journal‎

‎Legend of Istoria Journal Adventurer Edition - Adventure-Ready Guided Journal to Explore Face Challenges & Embark on a Quest - Bold Self Help Journal w/ Daily Art Colorable Pages & an Istoria Map‎

‎Good. Exact ISBN match. Immediate shipping. No funny business. unknown‎

Referentie van de boekhandelaar : 9781639729340 ISBN : 1639729348 9781639729340