Marabout

2014 · Best.-Nr. 361529 — Norfolk United Kingdom : Caister Academic Press 2014. First Edition. Hardcover. As New. Large 8vo 9" - 10. Fine-looking structurally sound hardcover little discernible wear bright interior unmarked. Black and blue covers with title in white lettering on front cover and spine. From the publisher's blurb "In recent years we have accumulated a great deal of knowledge on the features associated with virulence of pathogenic E. coli. A large number of virulence genes have been identified and their products characterised. Great strides have been made in our understanding of the pathogenic mechanisms and the bacterium-host interaction. However much remains elusive in our understanding of pathogenicity at a cellular and sub-cellular level. This is largely due to E. coli genome's plasticity: it generates great variability and facilitates the rapid emergence of new pathogenic variants. Elucidating the mechanisms underlying the evolution of these pathogens and their interactions with the host are key stages for disease prevention. This book reviews the most important recent findings of the studies on pathogenic E. coli providing a timely overview of the field. Topics covered include: epidemiology of the disease in humans and animals and the biological mechanisms that shaped the pathogenic types of E. coli; shiga toxins; subtilase cytotoxin; cell cycle modulating toxins; the heat stable and heat labile enterotoxins; haemolysins; structural molecular and functional characteristics of A/E lesions; colonization factor antigens of ETEC; enteroaggregative adhesion; host cell invasion; and the development of vaccinal strategies to confront the burden of disease. Chapters are written from a molecular and cellular biology standpoint but also include discussions of the findings with a wider perspective including considerations on public health and the impact on animal productions. Essential reading for everyone working on these and related pathogens." Fifteen chapters by Rosangela Tozzoli and Flemming Scheutz Jacques G. Mainil and John M. Fairbrother Shana R. Leopold Ulrich Dobrindt Helge Karch and Alexander Mellmann Gene FerriesMaite Muniesa and Herbert Schmidt Samuel Juillot and Winfried Römer Adrienne W. Paton Hui Wang Valeria Michelacci Stefano Morabito and James C. Paton among others. Volume contains scholarly apparatus in the form of e.g. notes index and bibliography. x 1-304 pp pp. and with another section of color plates.Member I.O.B.A. C.B.A. and adherent to the highest ethical standards. Additional postage may be required for oversize or especially heavy volumes and for sets. Caister Academic Press hardcover