Canons

1915 · rif. 140943594 — New York: D. Appleton and Company 1915. First Edition. First edition. Signed by Walter Cannon on the front free endpaper "With cordial regards." xiii 311 pp. Bound in publisher's crimson cloth with gilt spine lettering. Very Good with darkened spine lettering worn tips diagonal crease to ffep lacking dust jacket. Quite rare signed. The author was an American physiologist who riginated the concept of homeostasis. This particular work introduced the world to the "fight or flight response." According to an article on him in BrainImmune an online neuroendocrine immunology review "He asserted that not only physical emergencies such as blood loss from trauma but also psychological emergencies such as antagonistic encounters between members of the same species evoke release of adrenaline into the bloodstream. To Cannon the body"s responses to 'fight' are the same as those to 'flight.' Adrenaline exerts several important effects in different body organs all of which from Cannon"s point of view maintain homeostasis in fight-or-flight situations. In the skeletal muscle of the limbs adrenaline relaxes blood vessels increasing local blood flow." Garrison Morton 1200. D. Appleton and Company unknown